Description

Cagrilintide is a long-acting acylated amylin analog designed for investigational use in metabolic research. Amylin is a peptide hormone co-secreted with insulin from pancreatic beta cells that plays important roles in glucose homeostasis and appetite regulation. Cagrilintide has been engineered with structural modifications that extend its pharmacological half-life, making it suitable for less frequent administration in research protocols. In preclinical and clinical research, Cagrilintide has been studied for its effects on satiety signaling, gastric emptying, and glucagon suppression. The compound operates through amylin receptor agonism, modulating central appetite pathways in the brainstem and hypothalamus. It is of particular interest in combination studies with GLP-1 receptor agonists for synergistic metabolic effects. Supplied as a lyophilized powder. For research use only.